Impact of adjuvant chemotherapy on survival after pathological complete response in rectal cancer: a meta-analysis of 31,558 patients.

Francisco Cezar Aquino de Moraes Francinny Alves Kelly Maria Eduarda Cavalcanti Souza Rommel Mario Rodríguez Burbano

Published in: International journal of colorectal disease (2024)

This systematic review and meta-analysis found a significant difference in favor of the ACT group in terms of survival after pCR. Therefore, the administration of this treatment as adjuvant therapy should be encouraged in clinical practice.

Keyphrases

rectal cancer
end stage renal disease
clinical practice
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
squamous cell carcinoma
patient reported outcomes
radiation therapy
combination therapy