Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function.
Emily R WattsJoseph WillisonSimone ArientiPranvera SadikuPatricia CoelhoManuel A Sanchez-GarciaAiliang ZhangFiona MurphyRebecca DickinsonAnanda MirchandaniTyler MorrisonAmy LewisWesley VermaelenBart GhesquierePeter CarmelietMassimilliano MazzonePatrick H MaxwellChristopher W PughDavid DockrellMoira K B WhyteSarah R WalmsleyPublished in: Wellcome open research (2024)
PHD3 deficiency drives a favourable neutrophil phenotype in infection and, as such, is an important potential therapeutic target.
Keyphrases