Molecular characterization of the apoptosis-related SH3RF1 and SH3RF2 genes and their association with exercise performance in Arabian horses.
Katarzyna Ropka-MolikM Stefaniuk-SzmukierK PiórkowskaT SzmatołaM Bugno-PoniewierskaPublished in: BMC veterinary research (2018)
The present study showed the supposed regulation mechanism of exercise-induced apoptosis in horses at the molecular level. The identified SH3RF2: c.796 T > C missense variant was associated with selected racing performance traits, which is important information during the evaluation of horses' exercise predisposition. The association results and frequencies of the CT and TT genotypes suggest the possibility of using SH3RF2 variant in selection to improve the racing performance of Arabian horses.
Keyphrases
- induced apoptosis
- endoplasmic reticulum stress
- high intensity
- oxidative stress
- physical activity
- resistance training
- genome wide
- signaling pathway
- computed tomography
- healthcare
- cell death
- intellectual disability
- dna methylation
- gene expression
- magnetic resonance
- cell cycle arrest
- contrast enhanced
- health information
- transcription factor
- genome wide analysis