PIK3CA mutations early persistence in cell-free tumor DNA as a negative prognostic factor in metastatic breast cancer patients treated with hormonal therapy.

William JacotFlorence DalencEvelyne Lopez-CrapezLeonor ChaltielAnna DurigovaNathalie GrosNicolas LozanoJean-Louis LacazeStéphane PouderouxLaurence GladieffGilles RomieuHenri RochéThomas FilleronPierre-Jean Lamy

Published in: Breast cancer research and treatment (2019)

NCT01612871, registered on June 6th, 2012; https://clinicaltrials.gov/ct2/show/NCT01612871 .

Keyphrases

cell free
prognostic factors
metastatic breast cancer
circulating tumor
computed tomography
image quality
contrast enhanced
dual energy
polycystic ovary syndrome
magnetic resonance imaging
type diabetes
protein kinase
bone marrow
stem cells
mesenchymal stem cells
single molecule
circulating tumor cells
nucleic acid