Phenotypic and genotypic profile of ceftolozane/tazobactam-non-susceptible, carbapenem-resistant Pseudomonas aeruginosa.

Christian M GillDavid P Nicolaunull null

Published in: The Journal of antimicrobial chemotherapy (2022)

Ceftazidime/avibactam remained active in vitro against the majority of ceftolozane/tazobactam-NS, MBL-negative P. aeruginosa. Ceftazidime/avibactam was highly active against isolates harbouring GES and KPC β-lactamases. These data highlight the potential clinical utility of genotypic profiling as well as the need to test multiple novel agents when carbapenem-resistant P. aeruginosa are encountered.

Keyphrases

gram negative
multidrug resistant
klebsiella pneumoniae
pseudomonas aeruginosa
acinetobacter baumannii
drug resistant
cystic fibrosis
electronic health record
single cell
biofilm formation
big data
human health
genetic diversity
artificial intelligence
risk assessment
zika virus
candida albicans