Neurofilament light chain as a biomarker in neuromyelitis optica spectrum disorder: a comprehensive review and integrated analysis with glial fibrillary acidic protein.

Sohyeon Kim Jae-Joon Lee Jin-Sung Park Minsung Kang Hung Youl Seok

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

NfL and GFAP hold promise as biomarkers for NMOSD, demonstrating their usefulness in distinguishing patients from healthy individuals, assessing disease severity, and possibly reflecting treatment response. However, it is important to recognize that NfL and GFAP may, at some point, have different roles.

Keyphrases

spectrum disorder
end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
cerebrospinal fluid
ionic liquid
binding protein
patient reported outcomes
big data
deep learning