Increased fT4 concentrations in patients using levothyroxine without complete suppression of TSH.
Heleen I JansenMarijn M BultPeter H BisschopAnita BoelenAnnemieke C HeijboerJacquelien J HillebrandPublished in: Endocrine connections (2023)
High fT4 without suppressed TSH concentrations can mainly be explained by L-T4 intake. Physicians and laboratory specialists should be aware of this phenomenon to avoid questioning the assay's performance or unnecessarily adapting the L-T4 dose in patients.