Hematopoietic cell transplantation for asymptomatic X-linked lymphoproliferative syndrome type 1.
Akihiro TamuraSuguru UemuraNobuyuki YamamotoAtsuro SaitoAiko KozakiKenji KishimotoToshiaki IshidaDaiichiro HasegawaHaruka HirokiTsubasa OkanoKohsuke ImaiTomohiro MorioHirokazu KaneganeYoshiyuki KosakaPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2018)
We describe a case of an asymptomatic patient with XLP1, who successfully underwent unrelated BMT with RIC regimen consisting of fludarabine, melphalan, and 3 Gy TBI. That was well tolerated and successfully generated complete chimerism in every subpopulation. This case delineates the option of allogeneic hematopoietic cell transplantation even in asymptomatic patients with XLP1.