The immune microenvironment characterisation and dynamics in hormone receptor-positive breast cancer before and after neoadjuvant endocrine therapy.

Gizem OnerGlenn BroeckxChristophe Van BerckelaerKaren ZwaenepoelSevilay AltintasZafer CanturkWiebren TjalmaZwi BernemanMarc PeetersPatrick PauwelsPeter A van Dam

Published in: Cancer medicine (2023)

The immune microenvironment plays an important role in ER+/HER-2 negative BC. NET influences the composition and functional state of the infiltrating immune cells. Furthermore, changes in the immune microenvironment are also associated with treatment response.

Keyphrases

positive breast cancer
stem cells
lymph node
rectal cancer
cell therapy
replacement therapy