Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Breast Cancer Effect via miR-200c-PDE7B/PD-L1-AKT/MAPK Axis.

Yue YangTing FangYi-Lan CaoYa-Xin LvQing-Qi ChangDan-Dan Zhang

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

This study implicates that EA11 prevents breast tumor development by interfering with the miR-200c-PDE7B/PD-L1-AKT/MAPK axis. EA11 may represent a potential therapeutic candidate for breast cancer.

Keyphrases

cell proliferation
signaling pathway
pi k akt
long non coding rna
long noncoding rna
oxidative stress
ionic liquid
mouse model
young adults
childhood cancer