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How herpesviruses pass on their genomes.

Anna K SerquiñaJoseph M Ziegelbauer
Published in: The Journal of cell biology (2017)
Herpesvirus genomes exist and replicate as episomes inside the host cell nucleus during latent infection. Chiu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201702013) find that unlike Epstein-Barr virus, which partitions viral genomes faithfully during cell division, Kaposi's Sarcoma-associated herpesvirus clusters viral genomes into loci that are distributed unequally to daughter cells.
Keyphrases
  • epstein barr virus
  • single cell
  • cell therapy
  • sars cov
  • stem cells
  • induced apoptosis
  • gene expression
  • genome wide
  • cell proliferation
  • bone marrow
  • oxidative stress