Association of Inadequately Low Left Ventricular Mass with Enhanced Myocardial Contractility in Severe Degenerative Aortic Stenosis.
Bernadeta ChyrchelDorota DługoszKlaudiusz BoltOlga KruszelnickaArtur DziewierzJolanta ŚwierszczEwa Wieczorek-SurdackaTomasz HryniewieckiAndrzej SurdackiPublished in: Journal of clinical medicine (2018)
Inadequately low LVM relative to the individual hemodynamic load could potentially reflect a different mode of the LV response to severe AS, associated with enhanced load-independent LV systolic performance, i.e., better LV contractility. If confirmed in a large series of patients, our small preliminary study may add to the possible mechanisms of a previously reported counterintuitive tendency of a lower, not higher, risk of adverse outcome in patients with low LV mass despite severe AS. Prospective studies are warranted, in order to determine a potential utility of LVM inadequacy in the risk stratification of patients with AS.
Keyphrases
- left ventricular
- aortic stenosis
- ejection fraction
- aortic valve replacement
- heart failure
- transcatheter aortic valve implantation
- early onset
- transcatheter aortic valve replacement
- hypertrophic cardiomyopathy
- end stage renal disease
- aortic valve
- acute myocardial infarction
- cardiac resynchronization therapy
- left atrial
- newly diagnosed
- mitral valve
- prognostic factors
- blood pressure
- chronic kidney disease
- coronary artery disease
- smooth muscle
- peritoneal dialysis
- atrial fibrillation
- case control
- percutaneous coronary intervention