Levels of preoperative cerebrospinal fluid pro-inflammatory mediators and chronic pain after total knee arthroplasty surgery.
Jungo KatoReiko MuraseRie MinoshimaFanglin LuTomoko ToramaruYasuo NikiShizuko KosugiHiroshi MorisakiPublished in: Acta anaesthesiologica Scandinavica (2023)
We identified the CSF fractalkine level as a potential predictor for CPSP severity following TKA surgery. In addition, our study provided novel insights into the potential role of neuroinflammatory mediators in the pathogenesis of CPSP.