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Salvage resection of recurrent previously irradiated brain metastases: tumor control and radiation necrosis dependency on adjuvant re-irradiation.

Jessica A WilcoxSamantha BrownAnne S ReinerRobert J YoungJustin ChenTejus A BaleMarc K RosenblumWilliam C NewmanCameron W BrennanViviane TabarKathryn BealKatherine S PanageasNelson S Moss
Published in: Journal of neuro-oncology (2021)
In this largest-known series evaluating SR outcomes in histopathologically-confirmed rBrM, we identify a significant LR risk that may be reduced with adjuvant PSRT and with minimal symptomatic RN. Prospective analysis is warranted.
Keyphrases
  • brain metastases
  • small cell lung cancer
  • early stage
  • radiation therapy
  • adipose tissue
  • insulin resistance