Salvage resection of recurrent previously irradiated brain metastases: tumor control and radiation necrosis dependency on adjuvant re-irradiation.

Jessica A WilcoxSamantha BrownAnne S ReinerRobert J YoungJustin ChenTejus A BaleMarc K RosenblumWilliam C NewmanCameron W BrennanViviane TabarKathryn BealKatherine S PanageasNelson S Moss

Published in: Journal of neuro-oncology (2021)

In this largest-known series evaluating SR outcomes in histopathologically-confirmed rBrM, we identify a significant LR risk that may be reduced with adjuvant PSRT and with minimal symptomatic RN. Prospective analysis is warranted.

Keyphrases

brain metastases
small cell lung cancer
early stage
radiation therapy
adipose tissue
insulin resistance