Metagenomic sequencing reveals time, host, and body compartment-specific viral dynamics after lung transplantation.
Stefanie WidderIrene GörzerBenjamin FriedelNina RahimiStefan SchwarzPeter JakschSylvia KnappElisabeth Puchhammer-StöcklPublished in: Microbiome (2022)
In summary, the detailed analysis of virome dynamics after lung transplantation revealed host, body compartment, and time-specific dependency patterns among viruses. Furthermore, our results suggested genetic adaptation to the host microenvironment at the level of the virome and support the hypothesis of functional complementarity between Anellovirus groups and other persistent viruses. Video abstract.