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Diagnostic implication of thyroid spherules for cytological diagnosis of thyroid nodules.

Heeseung SohnKennichi KakudoChan-Kwon Jung
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2024)
Our results suggest that the presence of thyroid spherules in FNA specimens can serve as a highly specific marker for benign thyroid conditions. The prevalence of spherule detection is strongly influenced by the cellularity. In cases with moderate to high cellularity, the identification of spherules can assist the cytopathologists in diagnosing thyroid FNA cases as benign.
Keyphrases
  • fine needle aspiration
  • high intensity
  • label free
  • bioinformatics analysis