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Sublimation application of 5-chloro-2-mercaptobenzothiazole matrix for matrix-assisted laser desorption/ionization mass spectrometry imaging of mouse kidney.

Maryam Yousefi-TaemehErgi DuliLaurentiu G DabijaMathieu LemaireDemian Rocha Ifa
Published in: Rapid communications in mass spectrometry : RCM (2023)
We demonstrate that samples prepared for MALDI-MSI using sublimation to apply the CMBT matrix yield high-quality mass spectrometric images of mouse kidney sections. We also provide data for the impact of various experimental parameters on image quality (e.g., temperature, time, matrix thickness, and spatial resolution).
Keyphrases
  • mass spectrometry
  • image quality
  • high resolution
  • optical coherence tomography
  • liquid chromatography
  • deep learning
  • electronic health record
  • magnetic resonance imaging
  • gas chromatography
  • data analysis