Thrombotic microangiopathy after kidney transplantation: Analysis of the Brazilian Atypical Hemolytic Uremic Syndrome cohort.
Hong Si NgaLilian Monteiro Pereira PalmaMiguel Ernandes NetoIda Maria Maximina Fernandes-CharpiotValter Duro GarciaRoger KistSilvana Maria Carvalho MirandaPedro Augusto Macedo de SouzaGerson Marques PereiraLuís Gustavo Modelli de AndradePublished in: PloS one (2021)
The TMA graft loss in the absence of a specific complement-inhibitor was higher among the Brazilian cohort of kidney transplant patients. This finding reinforces the need of eculizumab use for treatment of aHUS kidney transplant patients. Cost optimization analysis and the early access to C5 inhibitors are suggested, especially in low-medium income countries.