A conceptual framework for predicting and addressing the consequences of disease-related microvascular dysfunction.
P Mason McClatcheyJefferson C FrisbeeJane E B ReuschPublished in: Microcirculation (New York, N.Y. : 1994) (2018)
The contributions of microvascular perfusion parameters to tissue-level solute flux can be described using a minimal mathematical model. Our results hold promise for informing therapeutic interventions targeting microvascular perfusion.