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Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions.

Tejas S KhireAlec T SalminenHarsha SwamyKilean S LucasMolly C McCloskeyRaquel E AjalikHenry H ChungThomas R GaborskiRichard E WaughAngela J GladingJames L McGrath
Published in: Cellular and molecular bioengineering (2020)
Overall, our results demonstrate the potential of the μSiM-MVM in elucidating mechanisms involved in the pathogenesis of inflammatory disease, and provide evidence for a role for neutrophils in inflammation-associated endothelial barrier disruption.
Keyphrases
  • oxidative stress
  • endothelial cells
  • peripheral blood
  • climate change