External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children.
Alexander James MartinFabian Johannes Stanislaus van der VeldenUlrich von BothMaria N TsoliaWerner ZenzManfred SagmeisterClementien VermontGabriella de VriesLaura KolbergEmma J LimMarko PokornDace ZavadskaFederico M TorresIrene Rivero CalleNienke N HagedoornEffua UsufLuregn J SchlapbachTaco W KuijpersAndrew J PollardShunmay YeungColin G FinkMarie VoiceEnitan D CarrolPhilipp Kwame Abayie AgyemanAakash KhanijauStephane C PaulusTisham DeJethro Adam HerbergMichael LevinMichiel van der FlierRonald de GrootRuud Gerard Gerard NijmanMarieke Emontsnull nullPublished in: Archives of disease in childhood (2023)
Discrimination and calibration were good for bacterial pneumonia but poorer for other SBIs. The rule-out thresholds have the potential to reduce unnecessary investigations and antibiotics in this high-risk group.