Low- dose Apatinib promotes vascular normalization and hypoxia reduction and sensitizes radiotherapy in lung cancer.

Shanshan JiangYue ZhouLiqing ZouLi ChuXiao ChuJianjiao NiYida LiTiantian GuoXi YangZhengfei Zhu

Published in: Cancer medicine (2022)

Our data suggested that low- dose apatinib can successfully induce a vascular normalization window and function as a radio- sensitizer in the lung cancer xenografts model.

Keyphrases

low dose
high dose
early stage
radiation therapy
electronic health record
big data
oxidative stress
signaling pathway
data analysis