Gene mutations associated with thrombosis detected by whole-exome sequencing in paroxysmal nocturnal hemoglobinuria.

Liyan LiHonglei WangHui LiuZhaoyun LiuLijuan LiKai DingGuojin WangJia SongRong Fu

Published in: International journal of laboratory hematology (2019)

Genetic defects have a non-negligible effect on the incidence of thrombosis, and therefore, gene mutations maybe a genetic risk factor in PNH, which increase the incidence of thrombosis.

Keyphrases

risk factors
pulmonary embolism
genome wide
blood pressure
atrial fibrillation
copy number
obstructive sleep apnea
gene expression
depressive symptoms
catheter ablation