Salivary macrophage activation-related chemokines and mitogen-activated kinase kinase (MAPKK)-degrading proteolytic activity in type 1 diabetes mellitus.

Neslihan YilmazRecep PolatMervi GürsoyWendy KamanElif Gül AydinDareen FteitaDogukan YilmazFloris BikkerUlvi Kahraman Gursoy

Published in: Journal of periodontology (2023)

T1DM disrupts the salivary macrophage activation-related chemokine profile and dysregulates proteolytic MAPKK cleavage. These findings can be an outcome of the impaired systemic immune response in T1DM.

Keyphrases

protein kinase
immune response
adipose tissue
glycemic control
metabolic syndrome
inflammatory response
skeletal muscle