Histology of high-grade glioma samples resected using 5-ALA fluorescent headlight and loupe combination.
Alexandra M Giantini LarsenNatasha KharasDavid J PisapiaTheodore H SchwartzPublished in: Acta neurochirurgica (2023)
The headlamp/loupe device provides information about histology, cell density, and necrosis with similar PPV for tumor to the operative microscope. Safe complete resection of florescence has a PPV of 100% for radiographic GTR and should be the goal of surgery.