Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs.

Felipe Finger BanfiGabriela Camila KrombauerAmanda Luisa da FonsecaRenata Rachide NunesSilmara Nunes AndradeMillena Alves de RezendeMariana Helena ChavesEvaldo Dos Santos MonçãoAlex Guterres TarantoDomingos de Jesus RodriguesGerardo Magela Vieira JúniorWhocely Victor de CastroFernando de Pilla VarottiBruno Antônio Marinho Sanchez

Published in: The journal of venomous animals and toxins including tropical diseases (2021)

Dehydrobufotenin revealed to be a potential oral drug prototype presenting adequate antimalarial activity and absence of cytotoxicity, therefore should be subjected to further studies.

Keyphrases

single cell
drug induced
case report
case control
plasmodium falciparum
human health
adverse drug
emergency department
climate change