Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital-Preliminary Report.
Jakub KlimkiewiczDaniel PankowskiKinga WytrychiewiczAnna KlimkiewiczPaulina SiwikJoanna KlimczukArkadiusz LubasPublished in: Nutrients (2022)
Numerous data indicate the presence of cognitive impairment in people who have undergone COVID-19, often called COVID Fog (CF). This phenomenon persists even 6 months after infection, and its etiology and pathogenesis are not fully known. The aim of this article was to analyze the relationship among cognitive functioning, clinical data and nutrition indexes in patients discharged from the COVID-19 hospital of the Military Institute of Medicine, Warsaw, Poland. The sample comprised 17 individuals-10 women and 7 men, with ages of 65 ± 14 years. Cognitive impairment was measured with the use of the Montreal Cognitive Assessment (MoCA). The nutrition parameters included: hemoglobin, red blood cells, total cholesterol and its fractions, triglycerides, total protein, albumin, urea, creatinine, phosphates, calcium and sodium. The analysis showed that albumin concentration significantly correlated with the total MoCA score and especially with the short-term memory test score. Conversely, total cholesterol, and especially LDL concentrations, were highly and negatively associated with the MoCA score. In conclusion: markers of nutritional status are correlated with the severity of CF. Individuals with malnutrition or risk of malnutrition should be screened for CF. Further studies need to be performed in this area.
Keyphrases
- cognitive impairment
- sars cov
- coronavirus disease
- cystic fibrosis
- red blood cell
- healthcare
- low density lipoprotein
- end stage renal disease
- physical activity
- electronic health record
- ejection fraction
- big data
- adverse drug
- respiratory syndrome coronavirus
- emergency department
- mild cognitive impairment
- working memory
- pregnant women
- small molecule
- type diabetes
- skeletal muscle
- acute care
- amino acid
- pregnancy outcomes