Genome plasticity in Paramecium bursaria revealed by population genomics.
Yu-Hsuan ChengChien-Fu Jeff LiuYen-Hsin YuYu-Ting JhouMasahiro FujishimaIsheng Jason TsaiJun-Yi LeuPublished in: BMC biology (2020)
We report programmed DNA rearrangements in the P. bursaria macronuclear genome that allow cells to adjust gene copy number globally according to individual gene functions. Our results suggest that large-scale gene copy number variation may represent an ancient mechanism for cells to adapt to different environments.