Login / Signup

Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.

Yang YeSushi JiangChao ZhangYanxiang ChengHuan ZhongTao DuWenming XuRicardo AzzizHuidong ZhangXiaomiao Zhao
Published in: BioMed research international (2020)
Our study results provide mechanistic insight to the effect of BPDE on trophoblast dysfunction through enhanced cell apoptosis and inhibited migration, providing further experimental evidence to the causative links between BaP exposure and PRL.
Keyphrases
  • oxidative stress
  • endoplasmic reticulum stress
  • cell proliferation
  • signaling pathway
  • preterm birth
  • cell cycle arrest
  • pregnancy outcomes
  • life cycle