ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia-Reperfusion Injury and the Progression of Hepatic Metastases.

Celine TohmeTony HaykalRuiqi YangTaylor J AustinPatricia LoughranDavid A GellerRichard L SimmonsSamer Tohme Hamza O Yazdani

Published in: Cells (2024)

Our study highlights the effective protection of ZLN005 pretreatment as a therapeutic alternative in terms of acute liver injury and tumor metastases.

Keyphrases

liver injury
drug induced
ischemia reperfusion injury
liver failure
oxidative stress
skeletal muscle
nuclear factor
respiratory failure
immune response
aortic dissection
toll like receptor