Systematic risk analysis of radiation pneumonitis in breast cancer: role of cotreatment with chemo-, endocrine, and targeted therapy.
Julian MangesiusDanijela MinaschKatharina FinkMeinhard Nevinny-StickelPeter LukasUte GanswindtThomas SeppiPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2022)
Common treatment schedules in sequential chemoradiation following breast-conserving surgery only moderately increase lung toxicity, mainly as an asymptomatic complication, or to a minor extent, as transient pneumonitis ≤ grade 2. However, combined treatment with tamoxifen and the LHRH analog goserelin significantly increased the risk of pneumonitis in breast cancer patients after chemoradiation. Thus, closer surveillance of involved patients is advisable.
Keyphrases
- end stage renal disease
- locally advanced
- rectal cancer
- ejection fraction
- public health
- interstitial lung disease
- minimally invasive
- chronic kidney disease
- combination therapy
- photodynamic therapy
- prognostic factors
- oxidative stress
- squamous cell carcinoma
- neoadjuvant chemotherapy
- radiation therapy
- atrial fibrillation
- replacement therapy
- peritoneal dialysis
- acute coronary syndrome
- brain injury
- idiopathic pulmonary fibrosis
- positive breast cancer
- cerebral ischemia