The Importance of Kidney Medullary Tissue for the Accurate Diagnosis of BK Virus Allograft Nephropathy.
Brian J NankivellJasveen RenthawaMeena ShingdeAsrar KhanPublished in: Clinical journal of the American Society of Nephrology : CJASN (2021)
Active BK virus replication concentrated around the corticomedullary junction can explain the higher detection rates for BK virus allograft nephropathy with deep sampling. The current adequacy requirement specifying targeting medulla can be justified to minimize a missed diagnosis from undersampling.