Helicobacter Pylori -Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding.
Seo Hyun KimYoussef SolimanVikas N ChitnavisMaithili V ChitnavisPublished in: Case reports in gastrointestinal medicine (2023)
Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori -negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with H. pylori -negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the t (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy.
Keyphrases
- diffuse large b cell lymphoma
- helicobacter pylori
- weight loss
- end stage renal disease
- helicobacter pylori infection
- ejection fraction
- chronic kidney disease
- newly diagnosed
- early stage
- liver failure
- prognostic factors
- physical activity
- body mass index
- bariatric surgery
- mechanical ventilation
- case report
- peritoneal dialysis
- obese patients
- replacement therapy
- small bowel