Does breast-conserving surgery with radiotherapy in BRCA-mutation carriers significantly increase ipsilateral breast tumor recurrence? A systematic review and meta-analysis.

Miyako NaraSakiko IshiharaAtsuko KitanoNobuko TamuraTomoyuki ArugaDaiki KobayashiSeigo NakamuraHideko Yamauchi

Published in: Breast cancer (Tokyo, Japan) (2022)

The present study demonstrated that BRCA-mutation carriers with BCS have a higher risk of IBTR, which tended to persist for a long period and become more apparent with longer observation.

Keyphrases

minimally invasive
early stage
coronary artery bypass
radiation therapy
breast cancer risk
locally advanced
neoadjuvant chemotherapy
radiation induced
coronary artery disease
lymph node
acute coronary syndrome
rectal cancer