Nuclear factor kappa B regulated monocyte chemoattractant protein-1/chemokine CC motif receptor-2 expressing in spinal cord contributes to the maintenance of cancer-induced bone pain in rats.
Yungong WangHuadong NiHongbo LiHoushen DengLong S XuShijie XuYing ZhenHui ShenHuan PanMing YaoPublished in: Molecular pain (2018)
In conclusion, NF-кB signaling pathway regulates the expressions of MCP-1/CCR2-induced inflammatory factors in the spinal cord of CIBP rats.
Keyphrases
- nuclear factor
- spinal cord
- toll like receptor
- signaling pathway
- neuropathic pain
- high glucose
- diabetic rats
- oxidative stress
- spinal cord injury
- dendritic cells
- pi k akt
- chronic pain
- papillary thyroid
- endothelial cells
- inflammatory response
- transcription factor
- drug induced
- lps induced
- bone mineral density
- regulatory t cells
- cell proliferation
- binding protein
- postmenopausal women
- small molecule
- soft tissue
- induced apoptosis
- bone regeneration