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[Contribution of endopeptidases to changes in scleral biomechanics in axial elongation of the eye].

A G Matyushchenko
Published in: Vestnik oftalmologii (2021)
The article describes the main properties of the sclera in patients with axial eye elongation depending on the degree of axial myopia, and presents basic information on the structure, mechanism of action and regulatory activity of matrix metalloproteinases (MMPs). MMPs play the key role in the development of abnormal catabolism of extracellular matrix components of the fibrous capsule - the process leading to changes in scleral structure and biomechanical properties in eyes with anterior-posterior axis elongation.
Keyphrases
  • extracellular matrix
  • optical coherence tomography
  • transcription factor
  • finite element analysis
  • healthcare