Alterations in plasma cytokine levels in chinese children with autism spectrum disorder.
Chun-Chun HuXiu XuGuo-Liang XiongQiong XuBing-Rui ZhouChun-Yang LiQi QinChun-Xue LiuHui-Ping LiYun-Jun SunXiang YuPublished in: Autism research : official journal of the International Society for Autism Research (2018)
Alteration of immune system function is an important risk factor for autism spectrum disorder (ASD). Here we found that the levels of cytokines, including Eotaxin, TGF-β1 and TNF-α, are elevated in Chinese children with ASD, as compared to typically developing children. The change in TGF-β1 level was most prominent in boys, while that of Eotaxin was more significant in girls. These results provide evidence for changes in cytokine profile in Chinese children with ASD.