Real-world challenges in the diagnosis of primary progressive multiple sclerosis.
Katelijn M BlokJoost J F M SmoldersJoost van RosmalenCarine O Martins JarnaloBeatrijs WokkeJanet de BeukelaarPublished in: European journal of neurology (2023)
Accurate interpretation of the initial clinical course, consideration of alternative diagnoses, and a full diagnostic workup are the cornerstones of a PPMS diagnosis. When these conditions are met, the 2010 and 2017 McDonald criteria for PPMS perform similarly, emphasizing the importance of their appropriate application in clinical practice.