Simulating Colorectal Cancer Trials Using Real-World Data.
Zhaoyi ChenHansi ZhangThomas J GeorgeYi GuoMattia ProsperiSerena Jingchuan GuoDejana BraithwaiteFei WangWarren A KibbeLynne I WagnerJiang BianPublished in: JCO clinical cancer informatics (2022)
In this study, we simulated five CRC trials, and tested two simulation scenarios with several different configurations demonstrated that our simulations can robustly generate effectiveness and safety outcomes comparable with the original trials using real-world data.