Development of the gonadotropin-releasing hormone system.

Anne H Duittoz Paolo Emanuele Forni Paolo Giacobini Matan Golan Patrice Mollard Ariel L Negron Sally Radovick Susan Wray

Published in: Journal of neuroendocrinology (2022)

This review summarizes the current understanding of the development of the neuroendocrine gonadotropin-releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic communication during migration of the GnRH cells.

Keyphrases

induced apoptosis
pregnant women
minimally invasive
gene expression
genome wide
oxidative stress
transcription factor
endoplasmic reticulum stress
genome wide identification