Association between homocysteine and coronary artery disease-trend over time and across the regions: a systematic review and meta-analysis.
Sumit V UnadkatBijaya K PadhiAparna Varma BhongirAravind P GandhiMuhammad Aaqib ShamimNeelam DahiyaPrakasini SatapathySarvesh RustagiMahalaqua Nazli KhatibAbhay GaidhaneQuazi Syed ZahiruddinRanjit SahHashem Abu SerhanPublished in: The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology (2024)
Higher homocysteine levels might have a significant association with coronary artery diseases, but the certainty of evidence was rated low, owing to the observational nature of the studies, high heterogeneity, and publication bias. Within the population groups, Asian and African populations showed a greater strength of association than their European and American counterparts, and it also increased over the years.