Understanding inequities in precision oncology diagnostics.
Ritika DuttaMounica VallurupalliQuinn McVeighFranklin W HuangTimothy R RebbeckPublished in: Nature cancer (2023)
Advances in molecular diagnostics have enabled the identification of targetable driver pathogenic variants, forming the basis of precision oncology care. However, the adoption of new technologies, such as next-generation sequencing (NGS) panels, can exacerbate healthcare disparities. Here, we summarize data on use patterns of advanced biomarker testing, highlight the disparities in both accessing NGS testing and using this data to match patients to appropriate personalized therapies and propose multidisciplinary strategies to address inequities looking forward.
Keyphrases
- healthcare
- palliative care
- electronic health record
- end stage renal disease
- affordable care act
- ejection fraction
- copy number
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- big data
- quality improvement
- prognostic factors
- patient reported outcomes
- health insurance
- social media
- deep learning
- artificial intelligence
- health information