Role of DNA ploidy in diagnosis and prognosis of high-grade cervical intraepithelial neoplasia: A prospective cohort study.

Adriane PogereAne Francyne CostaAna Paula Beltrame Farina PasinatoMarcos José MachadoFabiana Botelho de Miranda OnofreAlexandre Sherlley Casimiro Onofre

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)

In relation to high-grade CIN diagnosis, DNA-ICM presented similar sensitivity and specificity to cytology and high-risk HPV test when associated with HPV 16. Regarding prognosis, this research certifies that aneuploidy is considered a predictor of more severe cervical injury.

Keyphrases

high grade
low grade
circulating tumor
cell free
single molecule
early onset
drug induced