Glucose Metabolism Parameters and Post-Prandial GLP-1 and GLP-2 Release Largely Vary in Several Distinct Situations: a Controlled Comparison Among Individuals with Crohn's Disease and Individuals with Obesity Before and After Bariatric Surgery.

Daniéla Oliveira MagroEverton CazzoPaulo Gustavo KotzeAna Carolina Junqueira VasquesCarlos Augusto Real MartinezElinton Adami ChaimBruno GelonezeJosé Carlos ParejaCláudio Saddy Rodrigues Coy

Published in: Obesity surgery (2018)

Obesity is associated with an inflammatory state comparable to the one observed in CD; inflammation may also be enrolled in the blockade of GLP-2. CD individuals present a more incretin-driven pattern of glucose metabolism, as a way to prevent hypoglycemia and compensate the carbohydrate malabsorption and GLP-2 blockade.

Keyphrases

type diabetes
insulin resistance
metabolic syndrome
weight loss
oxidative stress
weight gain
high fat diet induced
adipose tissue
body mass index
physical activity