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Serum bile acid measurements in women of European and South Asian ethnicity with or without gestational diabetes mellitus: A cohort study.

Josca Mariëtte SchoonejansHei Man FanAlice L MitchellAnita Lövgren-SandblomNithya SukumarNishanthi PeriyathambiYonas Ghebremichael-WeldeselassiePaul T SeedAntonio MolinaroHanns-Ulrich MarschallPonnusamy SaravananCatherine Williamson
Published in: BJOG : an international journal of obstetrics and gynaecology (2024)
Serum BA homeostasis in late gestation depends on body mass index and GDM in ethnicity-specific ways. This suggests ethnicity-specific aetiologies may contribute to metabolic risk in European and South Asian women, with the relationship between BAs and insulin resistance of greater importance in European women. Further studies into ethnicity-specific precision medicine for GDM are required.
Keyphrases
  • polycystic ovary syndrome
  • insulin resistance
  • pregnancy outcomes
  • pregnant women
  • type diabetes
  • adipose tissue
  • preterm infants
  • high fat diet
  • skeletal muscle
  • high fat diet induced