Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?

Stephanie W VredeHannah DonkersCasper ReijnenAnke SmitsNicole C M VisserPeggy M GeominiHuy NgoDennis van HamontBrenda M PijlmanMaria Caroline VosMarc P L M SnijdersRoy KruitwagenRuud L M BekkersKhadra GalaalJohanna M A Pijnenborg

Published in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2024)

Specific applied adjuvant treatment is needed if patients with anaemia have a reduced response to radiotherapy in EC. Prospective validation in a larger study cohort is required to verify anaemia as predictive biomarker for radiotherapy and to further evaluate the prognostic/predictive impact of anaemia in addition to the molecular subgroups.

Keyphrases

early stage
endometrial cancer
locally advanced
radiation induced
radiation therapy
iron deficiency
patients undergoing
rectal cancer
squamous cell carcinoma
combination therapy