Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis.

Iago Pinal-FernandezMaria Casal-DominguezAssia DerfoulKatherine PakFrederick W MillerJose César MilisendaJosep Maria Grau-JunyentAlbert Selva O'CallaghanCarme Carrion-RibasJulie J PaikJemima AlbaydaLisa Christopher-StineThomas E LloydAndrea M CorseAndrew Lee Mammen

Published in: Annals of the rheumatic diseases (2020)

Unique gene expression profiles in muscle biopsies from patients with MSA-defined subtypes of myositis and IBM suggest that different pathological mechanisms underly muscle damage in each of these diseases.

Keyphrases

gene expression
machine learning
skeletal muscle
dna methylation
interstitial lung disease
deep learning
genome wide
myasthenia gravis
single cell
systemic sclerosis