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Evidence of transmission of New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae through a gastrointestinal endoscope without an elevator channel.

Ann Fan YangAdrienne ShermanElizabeth NazarianWolfgang HaasJason MehrMichele PedraniThomas KirnSteven BrantSusan E BoruchoffKeith S KayeJohn P Mills
Published in: Infection control and hospital epidemiology (2024)
Although all endoscope cultures in our investigation were negative, the epidemiological link to gastrointestinal endoscopes, the high degree of relatedness via WGS, and the identification of asymptomatic NDM-KP colonization among patients exposed to shared endoscopes make the endoscopic mode of transmission most likely. This investigation highlights the probable transmission of NDM-KP via a gastroscope without an elevator channel, observed several months after an initial outbreak. We hypothesize that persistent mechanical defects may have contributed to the delayed device-related transmission of NDM-KP.
Keyphrases
  • klebsiella pneumoniae
  • multidrug resistant
  • escherichia coli
  • gram negative
  • drug induced
  • bioinformatics analysis