Pulmonary impairment independently determines mortality in critically ill patients with acute-on-chronic liver failure.
Martin Sebastian SchulzJan MengersWenyi GuAndreas DrolzPhilip G FerstlAlex AmorosFrank Erhard UschnerNora AckermannGeorg GuttenbergAlexander QueckMaximilian J BrolChristiana GrafPhilipp StoffersAnna-Lena Laguna de la VeraCarla CremoneseHans-Peter ErasmusMartin W WelkerAchim GrünewaldtVincente ArroyoJörg BojungaJavier FernandezStefan ZeuzemJohannes KluweKai-Hendrik PeifferChristoph WelschValentin FuhrmannGernot RohdeJonel TrebickaPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
This study highlights that not only pulmonary failure but also mechanical ventilation is associated with worse prognosis in ACLF patients. The grade of pulmonary impairment should be considered in the risk assessment in ACLF patients. The new score may be useful in the selection of patients for liver transplantation.