The influence of obesity on hydroxychloroquine blood levels in lupus nephritis patients.
Tatiana do Nascimento PedrosaLéonard de Vinci Kanda KupaSandra Gofinet PasotoNádia Emi AikawaEduardo Ferreira BorbaNilo Jc DuarteElaine Pires LeonClovis Artur Almeida da SilvaEloisa S BonfaPublished in: Lupus (2021)
Obese patients under the 2016-AAO prescribed dose of HCQ based on RBW with and without maximum daily dose restriction have a very high HCQ blood levels compared to non-obese patients, with a potential increased risk of ocular toxicity. The use of 2016-AAO dose of HCQ according to the ideal body weight for this group of patients should be considered.Clinicaltrials.gov #NCT0312243.
Keyphrases